I Giorni della Ricerca 2014: incontri nelle università

I Giorni della Ricerca 2014: incontri nelle università

Ogni giorno in Italia ci sono mille nuovi casi di cancro: un problema quotidiano che si ripete in centinaia di migliaia di famiglie che affrontano la malattia.
Oggi sappiamo curare buona parte di quei mille tumori al giorno, ed è grazie ai risultati della migliore ricerca selezionata per merito.
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Bioluminescent pancreatic cancer mouse models from genetically characterized primary cells

Bioluminescent pancreatic cancer mouse models from genetically characterized primary cells

A platform for drug discovery and toward personalized treatment in pancreatic cancer

AIRC Start-Up Unit Pisa: Dr. Niccola Funel, Dr. Elisa Giovannetti
Surgery-unit: Dr. N De Lio, Dr. V Perrone, Prof. U Boggi
Oncology-unit: Dr. S Caponi, Dr. E Vasile
Pathology-Unit: Dr. LE Pollina, Prof. D Campani
VUmc Amsterdam collaborators: Dr. T Würdinger, Prof. GJ Peters

Our AIRC-Start-Up research project (poster)

Pdf: Research project poster

La Dott.ssa Giovannetti eletta nel Consiglio Direttivo AISP

La Dott.ssa Giovannetti eletta nel Consiglio Direttivo AISP

Il  20 settembre 2014, la Dott.ssa Giovannetti è stata eletta quale membro del Consiglio Direttivo della della Associazione Italiana per lo Studio del Pancreas (AISP), per il triennio 2014-2016.

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AKT1 and SELP polymorphisms predict the risk of developing cachexia in pancreatic cancer patients

Avan A, Avan A, Le Large TY, Mambrini A, Funel N, Maftouh M, Ghayour-Mobarhan M, Cantore M, Boggi U, Peters GJ, Pacetti P, Giovannetti E
PLoS One. 2014 Sep 19;9(9):e108057. doi: 10.1371/journal.pone.0108057. eCollection 2014

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In vivo models as a platform for the discovery of new therapies in exocrine pancreatic neoplasms

In vivo models as a platform for the discovery of new therapies in exocrine pancreatic neoplasms

Elisa Giovannetti

Invited lecture on “New PDAC Models” at National Congress of the Italian Association for the study of the Pancreas (AISP) 2014

VU University Medical Center, Amsterdam, The Netherlands
AIRC‐Start‐Up, Pisa, Italy

XXXVIII National Congress of the Italian Association for the Study on Pancreas (AISP)
Bologna, 18th September 2014

Pdf: AISP2014

Molecular mechanisms underlying the role of microRNAs in the chemoresistance of pancreatic cancer

Garajova I, Le Large TY, Frampton AE, Rolfo C, Voortman J, Giovannetti E
BioMed Research International 2014;678401

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Press release of our Oncotarget paper for AIRC

Press release of our Oncotarget paper for AIRC

Galectina-4 emerge come nuovo regolatore nella metastatizzazione dei tumori del pancreas

La rapidità e l’aggressività della diffusione nei tessuti vicini, la refrattarietà alla chemioterapia standard e la tendenza a recidivare rendono il carcinoma del pancreas uno dei tumori più difficili e impegnativi da trattare.
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Galectin-4 expression is associated with reduced lymph node metastasis and modulation of Wnt/β-catenin signalling in pancreatic adenocarcinoma

Maftouh M, Belo AI, Avan A, Funel N, Peters GJ, Giovannetti E,* van Die I.*
Oncotarget 2014; 30;5(14):5335-49 (*these authors equally contributed to the study)

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Impact of MicroRNAs in Resistance to Chemotherapy and Novel Targeted Agents in Non-Small Cell Lung Cancer

Rolfo C, Fanale D, Hong DS, Tsimberidou AM, Piha-Paul SA, Pauwels P, Van Meerbeeck JP, Caruso S, Bazan V, Cicero G, Russo A, Giovannetti E
Curr Pharm Biotechnol. 2014; 15(5):475-85

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miR-211 modulates gemcitabine activity through downregulation of ribonucleotide reductase and inhibits the invasive behavior of pancreatic cancer cells

Maftouh M, Avan A, Funel N, Frampton AE, Fiuji H, Pelliccioni S, Castellano L, Galla V, Peters GJ, Giovannetti E
Nucleosides Nucleotides Nucleic Acids. 2014;33(4-6):384-93

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SNPs in PI3K–PTEN–mTOR and Brain Metastases in NSCLC – Letter

Avan A, Maftouh M, Avan A, Tibaldi C, Zucali PA, Giovannetti E
Clin Cancer Res 2014; 20(13):3623-4

Role of CYB5A in pancreatic cancer: correlation with clinical outcome and functional characterization in the modulation of autophagy and oncogenic phenotypes

Role of CYB5A in pancreatic cancer: correlation with clinical outcome and functional characterization in the modulation of autophagy and oncogenic phenotypes

Elisa Giovannetti, MD, PhD

Presentation on “Role of CYB5A in PDAC” at the American Pancreas Club Meeting 2014

Start-Up Unit, University of Pisa, Italy
VU University Medical Center, Amsterdam, The Netherlands

48th Annual Meeting of the Pancreas Club
Chicago, 2/3 May 2014

Pdf: AmericanPancreasClub2014

A polymorphism in the promoter is associated with EZH2 expression but not with outcome in advanced pancreatic cancer patients

Maftouh M, Avan A, Funel N, Paolicchi E, Vasile E, Pacetti P, Vaccaro V, Faviana P, Campani D, Caponi S, Mambrini A, Boggi U, Cantore M, Milella M, Peters GJ, Reni M, Giovannetti E
Pharmacogenomics 2014;15:609-18. 1

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Lactate dehydrogenase acetylation adds another piece to the puzzle of metabolic reprogramming in pancreatic cancer

Sciarrillo R, Minutolo F, Peters GJ, Giovannetti E
Translational Gastrointestinal Cancer. Vol 3, No 2 (April 2014)

Link: www.amepc.org/tgc/article/view/3706/4598
Free full PDF text: click here

CYB5A and autophagy-mediated cell death in pancreatic cancer

Giovannetti E, Giaccone G.
Autophagy 2014;10:697-8

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CYB5A role in pancreatic cancer prognosis and autophagy modulation

Giovannetti E,* Wang Q,* Avan A, Funel N, Lagerweij T, Lee JH, Caretti V, van der Velde A, Boggi U, Wang Y, Vasile E, Peters GJ, Wurdinger T, Giaccone G
JNCI – J Natl Cancer Inst. 2014;106(1):djt346. (*these authors equally contributed to the study)

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L’Azalea della Ricerca 2014

L’Azalea della Ricerca 2014

Domenica 11 maggio scegli l’Azalea della Ricerca di AIRC per festeggiare la mamma. L’unico regalo che da trent’anni rende i tumori femminili sempre più curabili.

L’Azalea della Ricerca vi aspetta domenica 11 maggio nelle vostre città per festeggiare la Mamma e trent’anni di progressi nella cura dei tumori femminili.

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All the publications authored by Dr. Giovannetti (until december 2019)

Publications

ORCID ID orcid.org/0000-0002-7565-7504
(see also: www.scopus.com)
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Press release mesothelioma grant

Press release mesothelioma grant

During the International Symposium at Alexandria (VA), the Mesothelioma Applied Research Foundation (Meso Foundation) has announced to fund a project on research on new drugs in mesothelioma by Dr. Giovannetti.
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Crizotinib inhibits metabolic inactivation of gemcitabine in c-Met-driven pancreatic carcinoma

Avan A, Caretti V, Funel N, Galvani E, Maftouh M, Honeywell RJ, Lagerweij T, Van Tellingen O, Campani D, Fuchs D, Verheul HM, Schuurhuis GJ, Boggi U, Peters GJ, Würdinger T, Giovannetti E
Cancer Res. 2013 Nov 15;73(22):6745-56

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