41st EORTC –PAMM winter meeting: February 13th-15th, 2020 in Stockholm

41st EORTC –PAMM winter meeting: February 13th-15th, 2020 in Stockholm

Our group actively participated to the EORTC–PAMM winter meeting 2020. The meeting was organised by the PAMM Scientific Committee and by the local organizers Prof. Stig Linder and Dr. Padraig D’Arcy in the wonderful auditorium of Karolinska Institute. continue reading →

Breastfeeding during R-CHOP chemotherapy: please abstain!

Breastfeeding during R-CHOP chemotherapy: please abstain!

Roma/Milano
The results of our study have been published in the “European Journal of Cancer” (2019 Aug 19;119:107-111), official journal Of the European Organization for Research and Treatment of Cancer (EORTC). continue reading →

The dichotomous role of the glycolytic metabolism pathway in cancer metastasis: Interplay with the complex tumor microenvironment and novel therapeutic strategies

The dichotomous role of the glycolytic metabolism pathway in cancer metastasis: Interplay with the complex tumor microenvironment and novel therapeutic strategies

Pisa,
The review written by the Btissame El Hassouni (PhD student, Dept. Medical Oncology, VUmc) on the role glycolytic metabolism pathway (and new anticancer agents targeting this pathway has been published in Seminars of Cancers Biology continue reading →

Role of c-MET Inhibitors in Overcoming Drug Resistance in Spheroids of Human PDAC and Stellate Cells

Role of c-MET Inhibitors in Overcoming Drug Resistance in Spheroids of Human PDAC and Stellate Cells

Shiraz,
Our collaborative paper with Prof. Firuzi (University of Shiraz, Iran) and the PhD student Pei Pei Che (Department of Radiobiology, VUmc) on the role of c-MET Inhibitors in Overcoming Drug Resistance in Spheroids of Human PDAC and Stellate Cells has been published at continue reading →

Quei cinque mesi che mi hanno fatto capire che avrei fatto il ricercatore

Quei cinque mesi che mi hanno fatto capire che avrei fatto il ricercatore

Amburgo,
Intervista del Dr. Filippo Cortesi (Universitaetsklinikum Hamburg-Eppendorf, Amburgo) che ha vinto una pretigiosa borsa iCARE AIRC e ricorda la nostra collabotrazione durante la sua internship come studente. continue reading →

Dr. Giovannetti at the congress “In squadra si può vincere”, Carrara

Dr. Giovannetti at the congress “In squadra si può vincere”, Carrara

Carrara,
Dr. Giovannetti participated to the congress organized by Dr. Mambrini on the role of a multidisciplinary approach for the treatment of pancreatic cancer. continue reading →

EORTC-PAMM 2019: Cancer Pharmacology Lab actively participated to the “Educational Course” and Dr. Giovanna Li Petri and Dr. Ingrid Garajova won the awards for their poster and oral presentation”

EORTC-PAMM 2019: Cancer Pharmacology Lab actively participated to the “Educational Course” and Dr. Giovanna Li Petri and Dr. Ingrid Garajova won the awards for their poster and oral presentation”

Verona,
For the first time the EORTC-PAMM group organized an educational course on “(pre)clinical pharmacology of anticancer drugs
continue reading →

Giorni della ricerca 2018: La dottoressa Elisa Giovannetti al Quirinale per la cerimonia AIRC.  Dr. Giovannetti participates at the ceremony of the Italian Association for Cancer Research at Quirinale

Giorni della ricerca 2018: La dottoressa Elisa Giovannetti al Quirinale per la cerimonia AIRC. Dr. Giovannetti participates at the ceremony of the Italian Association for Cancer Research at Quirinale

Roma,
“Onorata di aver partecipato all’incontro con il presidente Mattarella al Quirinale, durante la Giornata della Ricerca sul Cancro. “I giovani che fanno il mestiere del ricercatore sono l’investimento più proficuo e produttivo per il futuro dell’Italia, ed il compito della politica, che ci ha accolto in questa sede, è cercare di agevolarci e di costruire possibilità perché possiamo lavorare al meglio. continue reading →

Key microRNAs controlling pancreatic cancer progression – our last collaborative study published in Nature Communications

Key microRNAs controlling pancreatic cancer progression – our last collaborative study published in Nature Communications

Ottaviani S, Stebbing J, Frampton AE, Krell J, de Giorgio A, Trabulo SM, Nguyen VTM, Magnani L, Giovannetti E, Funel N, Gress TM, Jiao LR, Lombardo Y, Heeschen C, Castellano L. TGF-ß induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling EMT and stemness. Nat Comm 2018;9(1):1845
www.ncbi.nlm.nih.gov/pubmed/29748571

Presse releases have been published in UK and the The Netherlands, as follows:
The pharmacology group has identified key microRNAs controlling pancreatic cancer progression – a study published in Nature Communications continue reading →

Press release of the Mesothelioma Applied Research Foundation on our Annals of Oncology article

Press release of the Mesothelioma Applied Research Foundation on our Annals of Oncology article

Washington,
A press release on the MARF website described our article published on Annals of Oncology:
www.ncbi.nlm.nih.gov/pubmed/28945836

“These findings identify for the first time PCFT (a protein) as a novel mesothelioma prognostic biomarker, prompting prospective trials for its validation.” continue reading →

Dr. Giovannetti received the Award of Excellence from the International Group pf Endovascular Oncology

Dr. Giovannetti received the Award of Excellence from the International Group pf Endovascular Oncology

Pesaro,
Dr. Giovannetti participated with a lecture on “Optimizing immunotherapy: Rationale for a combination therapy approach” to the 3th INTERNATIONAL COURSE OF ENDOVASCULAR ONCOLOGY: A GLANCE BEYOND YOUR PRACTICE continue reading →

Our News&Views paper on Nature Nanotechnologies

Our News&Views paper on Nature Nanotechnologies

Pisa/Amsterdam/Baltimore,
“A synthetic lethal bullet” by Christian Rolfo & Elisa Giovannetti has been published on Nature Nanotechnology continue reading →

Dr. Giovannetti at the EORTC ECI leadership programme

Dr. Giovannetti at the EORTC ECI leadership programme

Brussels,
The European Organization for Research and Treatment of Cancer (EORTC) has selected 34 young oncologists/researchers for the EORTC ECI leadership programme, focused on EORTC-specific themes, as well as specific leadership attributes, inspiring meeting with “thematic guests” and challenging tasks for shaping the future of EORTC. continue reading →

Cancer Cell paper on “Swarm Intelligence-Enhanced Detection of Non-Small-Cell Lung Cancer Using Tumor-Educated Platelets”

Cancer Cell paper on “Swarm Intelligence-Enhanced Detection of Non-Small-Cell Lung Cancer Using Tumor-Educated Platelets”

Amsterdam,
Important results of collaborative studies with the group of Prof. Wurdinger (Department of Neurosurgery, VU University Medical Center (VUmc), Cancer Center Amsterdam (CCA); Department of Neurology, Massachusetts General Hospital and Neuroscience Program, Harvard Medical School, Charlestown, MA, USA) have been published in Cancer Cell. continue reading →

Nele Van Der Steen obtained her PhD at the University of Antwerp

Nele Van Der Steen obtained her PhD at the University of Antwerp

Antwerp,
Our “Amsterdam/Antwerp-shared” student Nele Van Der Steen has successfully discussed her PhD Thesis on “The labyrinth of cMET and EGFR signaling in non-small cell lung cancer” at the University of Antwerp. continue reading →

Cancer Pharmacology Lab under the spotlight at the 2017 International Symposium on Malignant Mesothelioma

Cancer Pharmacology Lab under the spotlight at the 2017 International Symposium on Malignant Mesothelioma

Bethesda,
We were extremely pleased to participate to this important meeting where mesothelioma patients, scientists, caregivers, family members, bereaved, and medical professionals came together for conference sessions, socialization, award presentations, and advocacy. continue reading →

Dr. Chiara Caparello awarded for her presentation at the AISP Congress 2016

Dr. Chiara Caparello awarded for her presentation at the AISP Congress 2016

Roma,
Our collaborator Dr. Chiara Caparello has been awarded for the best presentation at the National Congress of the Italian Association for the Study of the Pancreas (AISP). The results of Dr. Caparello studies have been published in the following review and scientific paper: continue reading →

Ricerca sul cancro, dall’università alle scuole: un progetto per avvicinare alla ricerca medico-scientifica gli studenti delle superiori

Ricerca sul cancro, dall’università alle scuole: un progetto per avvicinare alla ricerca medico-scientifica gli studenti delle superiori

Il 28 aprile si è conclusa la prima fase di un progetto pilota che ha visto come protagonisti AIRC, il Liceo delle scienze applicate “Enrico Fermi” di Lucca ed il laboratorio “Cancer Pharmacology Lab, Airc Start-up Unit” dell’Università di Pisa. L’iniziativa è partita a novembre 2015, in occasione del mese della continue reading →

Al via il progetto “Diamante” per ottimizzare il trattamento dei tumori del pancreas

Al via il progetto “Diamante” per ottimizzare il trattamento dei tumori del pancreas

DIAMANTE, a pancreatic cancer treatment project, just launched under the Regione Toscana “Fas Grant”

www.nano.cnr.it/new151

Fra i sedici progetti recentemente selezionati dalla Regione Toscana per il Bando Fas Salute (“per sostenere la ricerca in materia di qualità della vita, salute, in campo biomedicale e industriale”), c’è un progetto pisano di diagnostica molecolare continue reading →

The blog of BELLBROOKLABS reported a long description of one of our latest studies

The blog of BELLBROOKLABS reported a long description of one of our latest studies

Our recent article has been described by Dr. Robert Lowery in an article entitled Lung Cancer Cells Use NF-κB Pathway to Subvert Third Generation EGFR Kinase Inhibitors, as follows: “One of these, gefitinib, was the second kinase inhibitor to be approved by the FDA, in 2003, for the treatment of non-small-cell lung cancer (NSCLC); a second EGFR inhibitor, erlotinib, was approved the continue reading →